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DIRECT REVERSAL

DIRECT REVERSAL OF DAMAGE

  • O6-methylguanine is repaired by the enzyme MGMT, which removes the Me group, becoming methylated itself (‘suicide’)
  • Some UV-induced lesions may be repaired by the process known as photoreversal.
http://meddev.uio.no/elaring/lcms13/ernaeringslaere/nutr-cancer-biology/illustrations/directreversal.JPG